Clin2
NCT06547840Likely a fitRecruiting

Study of MOv18 IgE for ovarian, endometrial, and breast cancers with a specific marker

Advanced Ovarian CancerPlatinum-resistant Ovarian CancerTriple Negative Breast Cancer (TNBC)Triple -Negative Breast CancerEndometrial CancerAdvanced Endometrial Cancer

Part of Cancer, Skin, Women’s health & pregnancy clinical trials.

This trial tests a new antibody treatment called MOv18 IgE for patients with advanced ovarian, endometrial, or triple-negative breast cancers that have a protein called folate receptor alpha (FRα) on their tumor cells. The goal is to see if the treatment is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
45 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be a woman aged 18 or older.
  • You have advanced ovarian, endometrial, or triple-negative breast cancer that has come back or spread.
  • Your tumor must have a specific marker (folate receptor alpha) on at least 5% of cells, confirmed by a test.
  • You must be willing to provide a tumor sample (either from a past surgery or a new biopsy) for testing.
  • You need to have a negative basophil activation test (BAT) before starting treatment.
  • You must be able to do daily activities with little help (ECOG score 0 or 1).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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