Study of PF-08634404 plus chemotherapy for advanced endometrial cancer
Treatments studied
Part of Cancer, Women’s health & pregnancy clinical trials.
This study tests a new drug (PF-08634404) combined with chemotherapy for women with advanced or recurrent endometrial cancer that is MMR-proficient. The goal is to see if this combination works better than standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 or older and not pregnant.
- Your endometrial cancer is advanced (Stage III with measurable disease, Stage IV, or has come back) and cannot be cured with surgery or radiation.
- Your tumor is a type called 'MMR-proficient' (pMMR) — this is checked by a central lab.
- You must be in fairly good health (able to do daily activities) and have adequate organ function.
- You have not had prior immunotherapy or anti-angiogenic therapy for your advanced cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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