Injectable treatment for low puberty hormone levels
Part of Hormones & metabolism clinical trials.
This trial tests an experimental medicine for teenage boys with a condition called hypogonadotropic hypogonadism, where the body doesn't make enough sex hormones. The treatment combines two hormone-based injections to help the testes grow and function, with a goal of improving puberty.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 14 to just under 18 years old at the time of signing up.
- Your bone age (a hand X-ray test) must be more than 12 years old.
- Your height must be at least 145 cm, and your BMI (body mass index) must be under 30.
- You need a confirmed diagnosis of a specific type of low sex hormone condition (idiopathic or congenital hypogonadotropic hypogonadism).
- You must have very small testicles (less than 4 mL each) as measured by ultrasound, and your blood tests must show very low levels of hormones (FSH, LH, and testosterone).
- You must be willing to use reliable contraception (like condoms) during the study and for 3 months after treatment.
- You must not have certain other medical conditions or take certain medications before the trial starts.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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