Clin2
NCT06566443Likely a fitRecruiting

Honokiol for early-stage lung cancer before surgery

Carcinoma, Non-Small-Cell Lung

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a natural compound called honokiol in people with early-stage non-small cell lung cancer who are scheduled for surgery. The goal is to see if honokiol can help shrink or control the tumor before it is removed.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
15 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have early-stage non-small cell lung cancer that can be removed with surgery.
  • You are at least 18 years old.
  • Your cancer can be measured on scans (RECIST criteria).
  • Your blood counts and organ function meet certain minimum levels.
  • You have not had other cancer treatments like chemotherapy or radiation in the last 2 weeks.
  • You are willing to follow the study schedule and attend all visits.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06221462Not yet recruiting· Phase 2
Sintilimab plus anlotinib before surgery for lung cancer

This trial tests a combination of two drugs (sintilimab and anlotinib) given before surgery to shrink tumors in people with early-stage lung cancer that can be removed. The goal is to see if this approach helps improve outcomes.

NCT06379087Recruiting· Phase 2
Radiation, immunotherapy and targeted therapy for early-stage lung cancer

This trial tests a combination of radiation therapy before surgery, followed by the immunotherapy drug tislelizumab and the targeted therapy drug anlotinib after surgery, for people with stage II to IIIA non-small cell lung cancer (NSCLC). The goal is to see if this approach can improve outcomes for patients whose tumors can be removed surgically.

Hangzhou, Zhejiang
NCT06977828Not yet recruiting· Phase 2
Tislelizumab, Anlotinib and Chemo Before Surgery for Lung Cancer

This trial tests a combination of three drugs (tislelizumab, anlotinib, and standard chemotherapy) given before and after surgery for people with stage II to IIIB non-small cell lung cancer that does not have certain gene mutations. The goal is to see if this approach can improve outcomes for patients who can have their tumor removed.

Nanjing, Jiangsu
NCT07089199Recruiting· Phase 2
Drug combo before surgery for stage III lung cancer

This trial tests a combination of three drugs (tislelizumab, anlotinib, and nab-paclitaxel) given before surgery for stage III lung cancer that can be removed. The goal is to see if this treatment helps shrink the tumor and improves outcomes.

Jinan, Shandong
NCT06492421Recruiting· Phase 2
Immunotherapy before surgery for lung cancer

This trial tests whether giving two immunotherapy drugs directly into the tumor before surgery can shrink non-small cell lung cancer and improve outcomes. It is for people with early-stage (IIIA) lung cancer who are candidates for surgery.

Guanzhou, Guangdong
NCT06893354Not yet recruiting· Phase 4
Lorlatinib before surgery for ALK-positive lung cancer

This trial tests lorlatinib as a treatment before surgery for people with a type of lung cancer called non-small cell lung cancer that has an ALK gene change (ALK-positive). The goal is to understand why some tumors respond and others may not, using advanced genetic tests.

Hear when a new Carcinoma, Non-Small-Cell Lung trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.