A new device for leaky mitral valves without open-heart surgery
Part of Heart & circulation clinical trials.
This trial tests a new device for people whose mitral valve leaks badly (grade 3+ or 4+) and who are not candidates for surgery. The device aims to fix the leak through a less invasive approach, and the study checks if it's safe and works well in daily life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your heart team has decided that open-heart surgery is not an option for you.
- You have a leaky mitral valve that is moderate to severe or severe (grade 3+ or 4+).
- You are on the best medical therapy for heart failure and have been for at least 3 months.
- You can do light to moderate daily activities without too much trouble (NYHA class II, III or IV that is not bedridden).
- Your heart's pumping strength is at least 30% (LVEF ≥ 30%).
- You have not had a stroke, heart attack, or other major heart procedure in the last 3 to 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a device placed during open heart surgery that tightens the leaking mitral valve to reduce blood flowing backward. It may help people whose valve leak is caused by heart muscle weakness and who are already having another heart surgery.
This trial tests a new device (SQ-Kyrin) to fix a leaky mitral valve without open-heart surgery. It is for people with heart failure whose valve leak causes symptoms, and who are not good candidates for traditional surgery.
This trial tests a new device designed to fix a leaky mitral valve in people with heart failure. It may help you breathe easier and feel less tired if your valve leak is severe and medicines have not been enough.
This trial tests a new catheter-based device to fix a leaky mitral valve without open-heart surgery. It is for people whose severe mitral regurgitation puts them at high risk for traditional surgery.
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
This trial is testing a new device to help people with severe mitral regurgitation (a leaky heart valve) who cannot have open-heart surgery or a valve clip. The device is placed using a thin tube through a blood vessel, and aims to improve symptoms and quality of life.
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