Combination therapy for CLDN18.2-positive advanced stomach cancer
Part of Cancer, Digestive system clinical trials.
This study tests a combination of three drugs (LM-302, Candonilimab, and Capecitabine) as the first treatment for advanced stomach cancer that has a specific protein (Claudin 18.2). It aims to see if the combination shrinks tumors and is safe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced stomach or gastroesophageal junction cancer that cannot be removed by surgery.
- Your tumor tests positive for a protein called Claudin 18.2 (at least 10% of cells).
- You have not had chemotherapy or radiation for advanced cancer before (prior treatment only allowed if it ended more than 6 months ago).
- You are generally well enough to be up and about (ECOG score 0 or 1).
- Your kidneys, liver, and blood counts are within safe ranges based on recent blood tests.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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