Clin2
NCT06093425Worth exploringNot yet recruiting

First-line combination treatment for stomach cancer with specific marker

Gastric CancerGastroesophageal-junction CancerAdvanced Cancer

Part of Cancer, Digestive system clinical trials.

This trial is testing a new combination of drugs (osemitamab, pembrolizumab, and chemotherapy) as the first treatment for advanced stomach cancer. It's for people whose tumors have a specific marker called Claudin 18.2, which might make the treatment more effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
820 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older
  • You must have stomach or gastroesophageal junction cancer that has spread and you haven't received treatment for it yet
  • Your tumor must test positive for a protein called Claudin 18.2 (a lab test will confirm this)
  • You need to be in fairly good health (able to do light activities)
  • You must provide a tumor tissue sample (from an old biopsy or a new one) for testing

View the official record on ClinicalTrials.gov

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Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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