Testing a new drug for advanced solid tumors
Part of Cancer clinical trials.
This trial is testing whether a new drug called CT7439 can help people with advanced solid tumors that have not responded to other treatments. It is a phase 1/2 study that also checks the drug's safety and how well it works.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a solid tumor that has spread locally or to other parts of the body and has no curative treatment available.
- You are well enough to carry out daily activities (ECOG score of 2 or less).
- You can take oral medications and are willing to keep a diary of your drug intake.
- You have not had treatment with a similar drug (CDK12/13 inhibitor) before.
- You have no active other cancer (except certain skin cancers or cervical pre-cancer) in the last 3 years.
- You have no brain metastases, active autoimmune disease, or severe infections.
- Your organ functions (liver, kidneys, bone marrow) are adequate.
- You are not pregnant or breastfeeding and agree to use effective contraception if applicable.
- You have not had certain medications or supplements that could interact with the study drug before starting.
- You have not had active hepatitis B or C, or HIV (with exceptions for well-controlled cases).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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