Pre-surgery radiation or chemoradiation for returning rectal cancer
Part of Cancer, Digestive system clinical trials.
This trial tests whether giving radiation (with or without chemo) before surgery can help people whose rectal cancer has come back in the pelvis. It aims to make the tumor removable and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old
- Your rectal cancer has returned in the pelvis but has not spread to other organs
- The tumor can potentially be removed with surgery
- You have not had radiation therapy in the last 6 months
- You have not had chemotherapy for metastatic cancer, though you may have had adjuvant chemo after a prior surgery
- You are in generally good health (able to do daily activities) and have adequate organ function
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial studies a combination of SBRT (a precise kind of radiation) and an immunotherapy drug (PD-1 antibody) for people whose rectal cancer has come back in the pelvis and cannot be removed by surgery. The goal is to see if this treatment can shrink the tumor or stop it from growing.
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