Exparrel block for knee replacement pain relief
Treatments studied
Part of Pain clinical trials.
This trial tests a special numbing injection called an EXPAREL IPSA block to see how well it controls pain after knee replacement surgery. It is for people with knee arthritis who are having their first knee replacement under spinal anesthesia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for a first-time total knee replacement on one knee.
- Your knee pain is caused by arthritis (wear and tear).
- You are in generally good health (ASA class 1, 2, or 3).
- Your body mass index (BMI) is between 18 and 40.
- You are not currently using strong opioid pain medications daily.
- You have not had prior open surgery on the same knee (tiny camera surgeries are okay).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing a long-acting numbing medicine called Exparel to see how well it controls pain after a specific knee surgery (MPFL reconstruction) in teens and young adults. It may help reduce the need for strong painkillers after the operation.
This study tests if a long-lasting numbing medicine called Exparel, given by the surgeon during knee replacement, helps control pain after surgery. It is for people having their first total knee replacement on one knee due to arthritis.
This study tests a new way to deliver pain medication during and after knee replacement surgery. Researchers compare injecting a long-acting numbing medicine (EXPAREL) directly into the knee joint versus spreading it through the surgical area, to see which method works better for pain control.
This Phase 2 study compares two ways to reduce pain after total knee replacement (TKA): a steroid-enhanced nerve block versus a numbing shot called Exparel. It aims to see which option improves comfort and recovery after surgery done with spinal anesthesia.
This trial compares two methods of pain control after ACL surgery: a long-lasting local anesthetic (Exparel) versus a nerve block. It aims to find which provides better pain relief and recovery.
This trial tests whether Exparel (a long-lasting numbing medicine) helps reduce pain after total shoulder replacement. It may help you feel more comfortable after surgery and potentially need less pain medicine.
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