Testing ONO-4538 for Rhabdoid Tumor
Treatments studied
Part of Cancer clinical trials.
This trial tests a new drug, ONO-4538, in people with rhabdoid tumors that have come back or spread and cannot be removed with surgery. It is for those who have already tried at least one chemotherapy treatment that did not work or caused side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 1 year old or older.
- Your rhabdoid tumor has come back, spread, or cannot be removed with surgery.
- You have tried at least one chemotherapy treatment that did not work or caused too many side effects.
- You do not have another active cancer.
- You do not have spinal tumors that need radiation or surgery during the trial.
- You do not have other brain or nerve problems (other than those from your tumor) that are not well controlled.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new drug (ONO-4538) for people with Richter's transformation, a rare and aggressive lymphoma that can happen to people with CLL or SLL. It aims to see if the drug can help when standard treatments have stopped working or aren't an option.
This trial tests a new drug, ONO-4685, for people with certain types of T cell lymphoma or chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) that has not responded to standard treatments or cannot tolerate them. The goal is to see if the drug is safe and tolerable.
This trial is for people who are already being treated with ONO-4538 (either alone or with other treatments) and can continue into an “extension/rollover” study. It checks how well ONO-4538 continues to work and is used safely over more time.
This trial tests an investigational drug called ONO-7429 for people with advanced or recurrent solid tumors that have not responded to standard treatments. The goal is to see if the drug can help control the cancer.
This trial tests a new drug called HRS-4508 for people with advanced or metastatic solid tumors that have not responded to standard treatments. The goal is to see if the drug is safe, how the body processes it, and if it helps shrink tumors.
This early-phase (Phase 1) study tests ONO-4685 in adults whose T-cell lymphoma has come back or did not respond to treatment. It aims to find a safe dose and see whether it can shrink lymphoma in people with limited options.
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