Hormone pills before prostate cancer surgery
Treatments studied
Part of Cancer, Kidney & urinary clinical trials.
This trial tests two oral hormone drugs (darolutamide and relugolix) given before prostate removal surgery for men with high-risk prostate cancer. The goal is to see if this combination shrinks the tumor and improves treatment outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have high-risk prostate cancer (Gleason score 4+3 or higher, with multiple positive biopsies or a PSA over 20).
- You are scheduled to have your prostate removed (radical prostatectomy).
- You are able to swallow pills and are generally healthy enough for daily activities (ECOG 0–1).
- You have not taken any similar hormone treatments (like Lupron or Xtandi) in the past year.
- You have not had a heart attack, stroke, or severe heart failure in the last 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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