Studying standard treatment response before rectal cancer surgery
Part of Cancer, Digestive system clinical trials.
This study looks at how rectal cancer responds to the usual chemotherapy and radiation given before surgery. It aims to learn if certain molecular features of your tumor can predict how well it responds to treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a type of rectal cancer called adenocarcinoma (the most common kind) that has not been treated yet with radiation to the pelvis.
- You are planning to get standard treatment that includes chemotherapy and radiation before surgery.
- Your tumor does not have certain genetic features (mismatch repair deficiency or HER2 amplification).
- You are willing to have an MRI, and if needed, a biopsy from inside the rectum (you cannot be on blood thinners for that).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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