Short-course radiation with immunotherapy and chemo for rectal cancer
Part of Cancer, Digestive system clinical trials.
This trial tests whether adding a new immunotherapy drug (cadonilimab) to standard chemoradiation before surgery helps patients with locally advanced rectal cancer. It aims to improve treatment outcomes by using a shorter course of radiation followed by a combination of the immunotherapy and chemotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 79 years old.
- You have been diagnosed with rectal adenocarcinoma (a type of rectal cancer).
- Your cancer is at stage T3-T4/N+ and has not spread to other organs (M0).
- You are able to provide a tumor tissue sample (from a previous biopsy or a new one).
- You are in good general health (able to perform daily activities without help).
- Your blood counts and organ function (kidney, liver, bone marrow) are within certain ranges.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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