First-in-human study of DS-2243a for advanced cancers
Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests a new drug called DS-2243a for people with advanced solid tumors that have stopped responding to standard treatments. It targets a specific protein found in some cancers, and you need to have a particular immune system marker for it to work.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have one of these cancers that has spread or cannot be removed: synovial sarcoma, myxoid/round cell liposarcoma, non-small cell lung cancer, or urothelial cancer.
- You have a specific immune marker called HLA-A*02 (a blood test can tell).
- You have tried at least one standard treatment for your cancer, and it either didn't work or caused side effects.
- You have a tumor that can be measured on a CT scan or MRI.
- You are in generally good health (able to do daily activities) and your organs are working well enough.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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