Immune system study for tear gland swelling in IgG4 disease
Part of Immune system & allergy clinical trials.
This study looks at why the immune system becomes overactive in a rare disease that causes swelling of the tear glands (IgG4-related ophthalmic disease). It aims to find better ways to understand and treat this condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have either IgG4-related ophthalmic disease with confirmed tear gland involvement, or drooping tear glands confirmed by biopsy and needing surgery.
- For IgG4-related disease: you need a biopsy showing specific patterns, plus high IgG4 levels in blood.
- You cannot have other autoimmune diseases like Sjögren's syndrome, lupus, or rheumatoid arthritis.
- You cannot have other eye conditions like lymphoma or inflammatory pseudotumor in the tear gland.
- You must not have any mental disorders, cancers, or other conditions that make study participation unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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