Testing a new eye drop for Sjögren's dry eye
Part of Bones, joints & muscles, Eyes & vision, Immune system & allergy, Mouth & dental, Skin clinical trials.
This trial tests a new eye drop made from a natural protein (rhPRG4) to see if it safely and effectively relieves dry eye symptoms in people with Sjögren's syndrome. You'll be randomly assigned to receive the study drop or a placebo (inactive) drop for several weeks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with Sjögren's syndrome for at least 3 months.
- You are between 18 and 75 years old.
- You have moderate to severe dry eye symptoms (like dryness, burning, or grittiness).
- You are currently using only artificial tears for your dry eye (no other prescription drops like Restasis or Xiidra).
- You have not had any eye surgery or used other eye treatments (like steroid drops, IPL, or punctal plugs) in the last 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests an exosome treatment for people with Sjögren's syndrome whose dry eye symptoms haven't improved with standard care like artificial tears or steroid drops. The goal is to see if this new approach can help relieve eye discomfort.
This trial tests a special contact lens made from stem cells to treat dry eye caused by Sjögren's syndrome. It may help if standard treatments like artificial tears or steroid drops haven't worked.
This study tests whether a new eye drop (rhPRG4) can safely reduce dry eye symptoms caused by graft-versus-host disease (GVHD). It compares the active drops to an inactive placebo to see if they provide better relief.
This trial tests a new eye drop gel (CsA-PG) for people with dry eye disease. Participants must have had dry eyes for at least 6 months and meet specific eye exam scores. The study checks if the gel can improve symptoms and eye health.
This study tests whether RCI001, a new eye drop treatment, can help people with dry eye disease. If you've had dry eye symptoms for at least 6 months and are interested in trying a new treatment, this trial may be for you.
This study tests a new treatment for dry eye disease caused by Sjögren's syndrome. It may help people who still have dry eye symptoms even when using artificial tears.
Hear when a new Sjögren's Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.