Nerve block with two drug mixes for pain after abdominal surgery
Treatments studied
Part of Brain & nervous system clinical trials.
This trial compares two different pain-relief mixtures injected near the spine to see which works better after open abdominal surgery. Both mixtures include the anesthetic bupivacaine, plus either dexmedetomidine or dexamethasone to extend pain relief.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are scheduled for open abdominal surgery (not laparoscopic).
- You have no known allergies or bad reactions to bupivacaine, dexmedetomidine, or dexamethasone.
- You do not have an infection where the needle will go in (near the spine).
- You do not have a history of chronic pain, psychological disorders, or serious liver or kidney disease.
- You are willing and able to follow study instructions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two ways to manage pain during and after lower back surgery: one uses an ultrasound-guided nerve block, the other uses a medication called dexmedetomidine. The goal is to see which provides better pain control with fewer side effects.
This study compares two numbing medicines (bupivacaine alone vs. bupivacaine plus dexmedetomidine) to see which provides better pain relief after abdominal surgery. If you are having a planned abdominal operation, this trial may help improve your recovery comfort.
This study compares two different pain-relieving nerve blocks given during open ventral hernia repair surgery. The blocks are injected near the abdominal wall muscles to reduce pain after surgery. The goal is to see which block works better.
This study tests two types of nerve blocks (Erector Spinae Plane Block and Lateral Transversus Abdominis Plane Block) to see which provides better pain relief after open appendectomy. This could help reduce pain and the need for stronger painkillers after surgery.
This trial tests a special nerve block (called an erector spinae plane block) with two added medicines—dexmedetomidine and dexamethasone—to see if it can improve pain and recovery after lumbar spine fusion surgery. It may help you need less pain medication and feel better sooner.
This study tests a nerve block (erector spinae plane block) to see if it helps reduce pain after laparoscopic abdominal surgery. If you're having keyhole surgery, you may receive the block along with standard anesthesia.
Hear when a new Analgesia, Postoperative trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.