Light therapy for advanced lung tumors
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a new way to destroy lung tumors using a light-activated drug (5-ALA) and a special light during a bronchoscopy (a tube placed into the lungs). It may be an option if standard treatments have not worked or are not suitable for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced or terminal lung cancer (either primary or that has spread to the lungs).
- Standard treatments like surgery, radiation, or chemo/immunotherapy/targeted therapy have either failed or are not right for you.
- Your tumor is 3 cm or smaller and can be clearly seen on a CT scan.
- Your tumor is not in an area that can be safely removed by surgery.
- You are in generally good health and able to care for yourself (ECOG score 0 to 2).
- You are not allergic to porphyrins, iodine contrast agents, or related substances.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new approach: taking immune cells from your own tumor (TILs), growing them in the lab, then giving them back to you along with the immunotherapy drug pembrolizumab. It is for people with advanced lung cancer who have run out of standard options.
This trial tests a new light-activated therapy (interstitial photodynamic therapy) after palliative radiation to shrink inoperable airway tumors and improve breathing. It is for people with solid cancers that block the airway from the outside and cannot be removed with surgery.
This trial tests a special dye that helps surgeons see tumors more clearly during surgery, followed by a light therapy to destroy any remaining cancer cells. It is for people with advanced or returning colorectal cancer who are already scheduled for surgery.
This trial tests whether a special dye can make cancer cells glow during a bronchoscopy, helping doctors see and biopsy tumors more precisely. It is for people with stage III lung cancer that cannot be removed by surgery and who have already completed chemoradiotherapy.
This trial tests a new way of giving radiation (in high and low doses) together with chemotherapy and immunotherapy to treat advanced non-small cell lung cancer. The goal is to see if this combination can shrink tumors and help patients live longer.
This trial tests a new light-based treatment that is given alongside standard chemotherapy and radiation for people with a type of brain tumor called 'butterfly glioblastoma'. The goal is to see if adding this therapy can improve outcomes for patients with this challenging condition.
Hear when a new Lung Cancer, Non-Small Cell trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.