Clin2
NCT06680245Possibly a fitNot yet recruiting

Effect of mitomycin-C on glaucoma valve surgery outcomes

Glaucoma

Treatments studied

Part of Eyes & vision clinical trials.

This study tests whether applying a medication called mitomycin-C during Ahmed glaucoma valve implant surgery helps improve the outcomes for patients with open-angle glaucoma. If you need this type of surgery, it may help reduce eye pressure more effectively or with fewer complications.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
144 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years of age or older.
  • You have a type of open-angle glaucoma, including ocular hypertension, pigmentary dispersion, or pseudoexfoliation.
  • Your eye pressure is above 16 mmHg on at least two visits that are at least one month apart.
  • Both of your eyes have vision of 20/200 or better.
  • You have not had prior glaucoma surgery, laser treatment for glaucoma, or long-term steroid use.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07036510Recruiting· Phase 1/Phase 2
Safety and effectiveness of a timolol eye implant for glaucoma patients having cataract surgery

This trial tests a sustained-release implant that delivers timolol, a medicine to lower eye pressure, for people with glaucoma or high eye pressure who are also having cataract surgery. The implant is placed during surgery and may provide long-term pressure control without daily eye drops.

Panama City
NCT05924477Recruiting
Compare glaucoma shunt options to prevent cell loss

This study compares a glaucoma drainage device approach to see which one better prevents loss of corneal cells after surgery. You may benefit by receiving close monitoring around the time of glaucoma surgery and helping doctors improve surgical choices.

San Francisco, California
NCT07073937Enrolling by invitation
Three-year results of combined microstent and canaloplasty surgery

This trial is checking how well a combined eye surgery (Hydrus microstent plus canaloplasty plus cataract surgery) works over 3 years. It looks at long-term safety and effect on eye pressure. It's for people with open-angle glaucoma who already had that specific combination of procedures.

Salt Lake City, Utah
NCT07143708Not yet recruiting
Comparing two glaucoma stents with or without amniotic membrane

This study looks at whether two types of tiny drainage stents (PreserFlo and XEN) work safely to lower eye pressure in glaucoma. Some patients will also receive an amniotic membrane (a thin tissue that helps healing) during the surgery, and researchers will compare outcomes.

NCT06844292Recruiting
Comparing two microglaucoma surgeries with cataract surgery

This study compares two different devices (MINIject® and Hydrus® Microstent) used in microinvasive glaucoma surgery, both done at the same time as cataract surgery. It aims to find which one works better at lowering eye pressure.

Graz, Styria
NCT06492538Recruiting
Eye changes after glaucoma angle surgery

This study looks at how your eye's drainage angle changes after glaucoma surgery. It helps doctors understand what happens to the front part of your eye after procedures like laser or surgery to open the drainage area.

Guangzhou, Guangdong

Hear when a new Glaucoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.