PIPOX02: A study of adding chemo spray to standard treatment
Part of Cancer, Digestive system clinical trials.
This trial compares standard chemotherapy alone to standard chemotherapy plus a special spray of chemotherapy during a short surgery (PIPAC) for colon cancer that has spread to the lining of the belly (the peritoneum) and cannot be removed with surgery. The goal is to see if adding the spray helps shrink or control the cancer better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have colon cancer that has spread to the lining of your belly and cannot be surgically removed.
- You are starting your first chemotherapy treatment for advanced colon cancer.
- You are in generally good health (able to do daily activities).
- You have had a surgery to look inside your belly within the last 4 weeks (or will have one).
- You do not have a bowel blockage that cannot be treated with medicine, or active bleeding in your digestive tract.
- You have not had another cancer in the last 3 years (except for certain skin cancers or cervical cancer).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This Phase 2 study tests whether spraying chemotherapy into the abdomen (through a small procedure) after colon cancer surgery can lower the chance the cancer comes back. It is meant for people with high-risk tumor features but who have had surgery and have no proven relapse yet.
This trial tests a new way to give chemotherapy by spraying it into the belly during a minimally invasive surgery. It is for people whose colon or rectal cancer has spread inside the belly (peritoneal metastasis) but not to other organs.
This trial tests a new way to give chemotherapy – as a fine mist sprayed directly into the belly during a short laparoscopy (keyhole surgery). It is for people whose stomach, pancreas, or colon cancer has spread to the lining of the belly, and who haven't had much chemotherapy before.
This trial tests a new way to give chemotherapy directly into the belly as a fine mist (called PIPAC) for people whose cancer has spread there. The goal is to see if it’s safe and helps shrink or control the cancer.
This trial tests a new way to deliver chemotherapy directly into the abdomen (called PIPAC) for people with cancer spread to the lining of the belly. It uses the drug mitomycin and is for patients who cannot have standard surgery or heated chemotherapy.
This trial tests a new way to deliver chemotherapy directly into the abdomen using a spray (called PIPAC) in people with stomach cancer that has spread to the lining of the belly. The aim is to see if it can help control the cancer with fewer side effects.
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