Clin2
NCT07271355Possibly a fitRecruiting

Pressurized chemo spray for appendix or colorectal cancer spread in abdomen

Metastatic Appendix CarcinomaMetastatic Colorectal CarcinomaMetastatic Malignant Neoplasm in the PeritoneumStage IV Appendix Carcinoma AJCC v8Stage IVC Colorectal Cancer AJCC v8Unresectable Colorectal Carcinoma

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a new way to deliver chemotherapy directly into the abdomen as a pressurized spray, using a drug called mitomycin. It is for people with appendix or colorectal cancer that has spread to the lining of the abdomen and cannot be removed by surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
129 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have appendix or colorectal cancer that has spread to the lining of your abdomen (peritoneal metastases).
  • You have had at least 4 months of first-line chemotherapy with oxaliplatin, or you stopped early due to side effects, or the cancer progressed on that treatment.
  • You are generally healthy enough for daily activities (ECOG performance status 0 or 1).
  • You do not have cancer spread outside the abdomen except for up to 5 small spots in the lung (each 1 cm or less).
  • You are not able to have surgery to remove the cancer in your abdomen.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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