Testing mifepristone for hard-to-treat PTSD in Dutch adults
Treatments studied
Part of Mental health clinical trials.
This study tests a new medicine (mifepristone) to see if it helps people with PTSD that hasn't improved after standard treatments. You must be fluent in Dutch and have tried at least two PTSD treatments, including trauma-focused therapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older and able to give consent.
- You must have a confirmed PTSD diagnosis with symptoms still moderate to severe (CAPS-5 score of 30 or more).
- You must have tried and not responded to at least two evidence-based PTSD treatments, including a full course of trauma-focused therapy.
- You cannot have bipolar disorder, a psychotic disorder, or current alcohol/drug dependence needing treatment.
- You must not be pregnant, breastfeeding, or planning pregnancy during the study. Women who can become pregnant must use condoms.
- You cannot take certain medications (e.g., strong antibiotic/antifungal drugs, St. John's wort, steroids) or grapefruit juice during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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