Clin2
NCT06695689Possibly a fitRecruiting

LM303 injection for advanced solid tumors

Solid Tumor

Part of Cancer clinical trials.

This trial tests an investigational treatment called LM303 for people with advanced solid tumors like melanoma, lung cancer, or cervical cancer. It uses your own immune cells (called TILs) to fight the cancer, so you need a tumor large enough for cells to be collected.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
10 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have advanced melanoma, non-small cell lung cancer, cervical cancer, or another solid tumor that hasn't responded to standard treatments or has no standard treatment.
  • You have at least one tumor that is large enough (more than 1.5 cm³) to be surgically removed or biopsied for TIL collection.
  • Your blood counts must be within certain ranges, including enough white blood cells and lymphocytes (a type of immune cell).
  • Your liver and kidney function must be adequate, and your heart must pump at least 50% of blood with each beat.
  • You must be in good daily health (ECOG score 0 or 1) and expected to live more than 3 months.
  • You cannot have active autoimmune disease, uncontrolled infections, or certain viruses like hepatitis or HIV.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06342336Recruiting· Phase 1
HS-IT101 injection for advanced solid tumors

This trial tests an experimental cell therapy (HS-IT101) for people with advanced solid tumors that have not responded to standard treatments. It uses immune cells from your own tumor to fight cancer, and researchers want to see if it is safe and effective.

Beijing, Beijing Municipality
NCT05831033Recruiting· Early Phase 1
Your own immune T-cells to treat advanced solid tumors

This early-phase study tests a treatment made from your own tumor-fighting immune cells (TIL cells) for advanced solid cancers that have worsened or no longer respond to standard therapy. The main goal is to learn whether it is safe and whether it can shrink tumors for people who have limited options.

Shanghai, Shanghai Municipality
NCT06468358Recruiting· Phase 1/Phase 2
LB1410 and LB4330 for advanced solid tumors

This trial tests a combination of two experimental drugs (LB1410 and LB4330) in people with advanced or metastatic solid tumors that have stopped responding to standard treatments or where no standard treatment exists. It aims to see if this combination can shrink tumors or slow their growth.

Shanghai, Shanghai Municipality
NCT06613152Not yet recruiting· Early Phase 1
HS-IT201 injection for advanced solid tumors

This trial tests an experimental cell therapy for people with advanced solid tumors that have not responded to standard treatments. The therapy uses immune cells from your own tumor, grown in the lab and given back to you, potentially to help your body fight the cancer.

NCT05366478Recruiting· Phase 1
LM103 for advanced solid tumors using donated immune cells

This Phase 1 study tests LM103 to treat advanced cancers that are not responding to standard treatment. It also looks at whether enough tumor tissue can be collected for immune cell testing, and focuses on safety at first.

Tianjin
NCT07310784Recruiting· Phase 2
Testing LM103 for advanced melanoma

This trial tests a new drug called LM103 for people with advanced melanoma who have already tried several standard treatments, including immunotherapy. The goal is to see if LM103 can help shrink tumors when other treatments have stopped working.

Beijing, Beijing Municipality

Hear when a new Solid Tumor trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.