Study of icalcaprant for bipolar depression
Part of Mental health clinical trials.
This study tests an oral medication called icalcaprant for adults with bipolar I or II who are currently in a depressive episode. The goal is to see if it reduces symptoms and whether it's safe when taken alongside your usual mood stabilizer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of bipolar I or II (without psychosis) and are currently in a depressive episode that started at least 4 weeks ago.
- You are on a stable dose of one mood stabilizer (lithium, valproate, or lamotrigine) for at least 28 days before starting the study.
- You have minimal manic symptoms (score of 12 or less on a standard manic symptoms scale).
- Your body mass index (BMI) is between 18 and 35.
- You are in generally good health, with no unstable medical conditions or recent history of certain cancers.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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