Isotretinoin for improving sperm count in infertile men
Treatments studied
Part of Women’s health & pregnancy clinical trials.
This study tests whether a medicine called isotretinoin (a form of vitamin A) can improve sperm count in men with low sperm counts. It aims to help couples who are having trouble getting pregnant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been trying to get pregnant with your partner for over a year without success
- Your sperm count is low (less than 10 million moving sperm per sample) on two tests a week apart
- You are a man between 21 and 55 years old
- You are not currently taking isotretinoin (Accutane) or vitamin A supplements
- You have no history of depression, suicidal thoughts, or other serious mental health issues
- You have no liver or kidney problems, and your blood fat levels are normal
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests two medicines—isotretinoin and human chorionic gonadotropin (hCG)—to see if they can improve sperm production in men with low sperm counts or no sperm due to certain causes. It might help if you haven't responded to other treatments before.
This study tests whether a dietary supplement can improve sperm health in overweight men with fertility issues. If you qualify, you would take the supplement for a period and your sperm quality would be monitored.
This trial tests whether a daily food supplement (with myo-inositol, N-acetyl-cysteine, zinc, and vitamins) can reduce sperm DNA damage. It enrolls men with higher-than-normal sperm DNA fragmentation, and it checks semen health during the study.
This study compares two different hormone treatments to see which one better improves sperm health and increases pregnancy chances in men with low or abnormal sperm. You'll receive either injections or pills designed to boost sperm production.
This study tests whether a weight-loss injection or a healthy lifestyle program can improve sperm quality and fertility in obese men with low sperm health. You would be randomly assigned to one of the two groups, and the study will track your progress over time.
This study tests whether a herbal supplement can improve sperm health (count, movement, and shape) in men with fertility problems. You'll need to have low sperm counts and be in general good health, and you'll be asked to follow a routine that includes avoiding ejaculation before tests.
Hear when a new Men with Infertility trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.