Blood markers to help diagnose fever and inflammation in children
Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.
This study looks at two substances in the blood (IL-18 and IL-18BP) to see if they can help doctors tell apart different causes of fever and inflammation in children. It might help find better ways to diagnose conditions like juvenile idiopathic arthritis and autoinflammatory diseases.
Summary written for real people, not researchers, by Clin2.
Who can take part
- The child must be between 2 and 18 years old.
- The child must have one of these: juvenile idiopathic arthritis, recurrent fever or autoinflammatory disease, another rheumatic disease, or a severe infection like sepsis or meningitis.
- Parents or legal guardians must sign a consent form.
- The child cannot be suspected of having rheumatic fever based only on heart or movement findings.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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