Testing drug levels to improve antibiotic therapy in liver transplant patients
Part of Digestive system, Infections clinical trials.
This trial checks if monitoring antibiotic levels in the blood can help doctors give the right dose to liver transplant patients with serious bacterial infections. The goal is to make the treatment work better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old and have had a liver transplant.
- You have a Gram-negative bacterial infection within the first 90 days after transplant.
- You are being treated with a beta-lactam antibiotic (like penicillin or cephalosporin).
- You have not received this antibiotic for less than 48 hours.
- Your infection is not resistant to all beta-lactam antibiotics.
- You are not in hospice care or have a do-not-resuscitate order.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether testing the fluid used to store donated organs can help doctors find and treat infections earlier, possibly leading to better outcomes after a liver or kidney transplant.
This study tracks antibiotic levels in your blood after a lung transplant to make sure the dose is right for you. It aims to improve how antibiotics are given to prevent infections during recovery.
This study tests whether giving antibiotics chosen specifically for your resistant bacteria before a liver transplant can prevent infections better than the usual standard antibiotics. It aims to improve recovery and lower the risk of serious infection after surgery.
This study looks at whether choosing antibiotics based on local hospital lab reports (antibiograms) works well for organ transplant patients who have a single bacteria in their bloodstream. It hopes to find the best way to treat these infections.
This study measures how antibiotic drugs called beta-lactams work in people with cirrhosis (liver damage). Researchers will check antibiotic blood levels to see if standard doses are right for cirrhotic patients or need adjustment.
This trial studies whether using a special test called mNGS to find the exact infection in donated organs helps doctors choose better antibiotics for patients after a liver transplant. It may help reduce infections and improve recovery.
Hear when a new Liver Transplant Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.