Adding antibiotics to first chemo for advanced colorectal cancer
Part of Cancer, Digestive system clinical trials.
This trial tests whether adding a short course of antibiotics to your standard first chemotherapy for stage 4 colorectal cancer can improve treatment. The antibiotics target certain gut bacteria that might affect how well the chemo works.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with stage 4 colorectal cancer that has spread to other parts of the body.
- Your cancer can be measured on scans (RECIST 1.1 criteria).
- You are about to start your first round of chemotherapy with a 5FU-based two-drug combination (for example, FOLFOX or FOLFIRI).
- You are generally able to care for yourself (ECOG performance status 0, 1, or 2).
- You have adequate blood counts and liver and kidney function, as shown by lab tests.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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