Penthrox vs placebo for sinus surgery pain
Treatments studied
Part of Ear, nose & throat clinical trials.
This trial tests if a pain reliever called Penthrox (methoxyflurane) works better than a placebo for pain during minor sinus procedures. If you are having a simple sinus surgery or coblation procedure, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 19 years old or older
- You are scheduled for a minor sinus surgery or coblation procedure
- You do not have cystic fibrosis
- You do not have a bleeding disorder or history of kidney or liver failure
- You have not used inhaled drugs (like cocaine) in the past 6 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether adding a special rinse with povidone-iodine and budesonide after sinus surgery helps reduce inflammation and improve symptoms in people with chronic sinusitis. It may help you recover better and have fewer sinus problems after your operation.
This study tests a new sinus stent that slowly releases medication to treat chronic sinusitis. It may reduce symptoms and help avoid repeated surgeries.
This study tests a special nose dressing that slowly releases a steroid to reduce inflammation and improve healing after sinus surgery for chronic sinusitis with or without nasal polyps.
This study tests a steroid-releasing implant placed during sinus surgery to help prevent inflammation and improve healing in patients with chronic sinus infections. If you're having sinus surgery in Japan, this trial may track how well the implant works for you.
This study tests a numbing medication (bupivacaine with epinephrine) injected during your first sinus surgery to see if it helps reduce pain after the procedure. It may be an option if you have not had sinus surgery before and are generally healthy.
This trial tests a pain-relief medicine called Penthrox (methoxyflurane) that you breathe in through a handheld inhaler. It is used alongside numbing medicine during common ear, nose, or throat procedures to help reduce pain and anxiety. The goal is to see if it works well and is safe for these procedures.
Hear when a new Chronic Rhinosinusitis (CRS) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.