TLR-4 in gum disease patients with kidney failure
Part of Kidney & urinary, Mouth & dental, Women’s health & pregnancy clinical trials.
This study looks at a specific immune marker (TLR-4) in people with gum disease, comparing those who also have end-stage kidney disease (on dialysis) to those who are otherwise healthy. The goal is to understand how gum disease might be different when kidney failure is also present.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 30 and 60 years old.
- You have been diagnosed with gum disease (periodontitis stage II or III).
- Either you are generally healthy with no other long-term illnesses and not on regular medications, OR you have end-stage kidney disease, are on dialysis, and have type 2 diabetes.
- You do not smoke.
- If you have kidney disease, you have not had a kidney transplant and have no other major illnesses besides diabetes.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a manuka honey mouth rinse can help treat gum disease in people who are on dialysis for kidney failure. If you have both kidney failure and gum disease, this study may offer a natural way to improve your oral health.
This study looks at the link between gum disease (periodontitis) and chronic kidney disease. It may help understand if treating one affects the other.
This study explores whether people with certain rare kidney diseases or chronic kidney problems have more gum disease than others. Researchers will examine your teeth and gums to understand the connection and help improve care for people with kidney conditions.
This trial tests whether a deep dental cleaning procedure can help slow the progression of advanced kidney disease in people with type 2 diabetes who are not yet on dialysis. It may be an option for those with moderate gum disease and at least 20 natural teeth.
This study looks at how diet affects the health of your gums in people with chronic kidney disease (CKD). It may help understand if certain foods can improve mouth health and overall well-being.
This study looks for new markers in the body that could help diagnose gum disease. It's for adults with mild gum problems who haven't had recent dental treatment or antibiotics.
Hear when a new Periodontitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.