Nebivolol for chest pain with normal coronary arteries
Part of Heart & circulation, Pain clinical trials.
This trial tests if the drug nebivolol reduces chest pain in people who have chest pain but no major blockages in their heart arteries. It looks at whether the small blood vessels in the heart are not working properly, which can cause symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have had chest pain or discomfort at least once a week for the past 3 months.
- Tests show no major blockages in your heart arteries (normal coronary angiogram with FFR > 0.80).
- A special test of the small heart blood vessels shows they do not open properly (CFR < 2.0 or IMR ≥ 25).
- You do not have certain heart conditions like very weak heart pumping (LVEF < 45%), recent heart stents, or heart surgery.
- You are not pregnant or breastfeeding, and you do not have severe kidney or liver disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at women who have chest pain but no major blockages in their heart arteries. It uses special tests to understand the cause and gives personalized treatment to help reduce symptoms and improve heart health.
This trial is testing a new way to diagnose problems in the small blood vessels of the heart that can cause chest pain even when the main arteries look clear. The test uses a special technique to measure how well these small vessels work, which could help find the cause of your symptoms.
This study compares two ways of testing the small blood vessels in the heart to understand chest pain when no major blockages are found. It may help doctors learn more about why you have chest pain and how to treat it.
This study tests whether taking an inorganic nitrate supplement can improve chest pain and blood flow in women who have chest pain but no blocked heart arteries. It may help if your heart's small blood vessels are not working properly.
This study looks at people who still have chest pain even though their coronary arteries are not blocked. It tests a non-invasive approach to better understand the cause of the pain, which may help tailor treatment.
This trial tests if beta-blocker medication improves blood flow and reduces resistance in the tiny blood vessels of the heart in people who have chest pain but no major blockages in their arteries.
Hear when a new ANOCA - Angina With Non-obstructive Coronary Arteries trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.