Nitrate treatment for chest pain with clear arteries
Part of Heart & circulation, Pain clinical trials.
This study tests whether taking an inorganic nitrate supplement can improve chest pain and blood flow in women who have chest pain but no blocked heart arteries. It may help if your heart's small blood vessels are not working properly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 or older.
- You have had chest pain or other signs of reduced blood flow to the heart, and a test within the last 2 years (like a heart catheterization or CT scan) showed no major blockages.
- You have been diagnosed with reduced blood flow in the small heart vessels (called coronary microvascular dysfunction) based on specific tests.
- You have never taken an SGLT2 inhibitor (a type of diabetes medicine).
- You are not currently taking nitroglycerin, other nitrates, certain erectile dysfunction drugs (like Viagra or Cialis), or allopurinol.
- You are not a smoker (or have not smoked in the last 5 years).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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