SSRI side effects genetics study

This trial studies whether genes (using a saliva sample) can help explain why some young people feel more “disinhibited” after taking antidepressants like SSRIs. If you’ve had depression, anxiety, or OCD and have used an SSRI, your information and genetics may help improve how antidepressants are chosen and monitored.

This research study examines how certain genes are expressed (turned on or off) in people with psychiatric conditions like bipolar disorder, depression, panic disorder, OCD, or schizophrenia. The study compares gene expression in patients with these conditions to healthy volunteers to better understand what happens at a biological level.

This trial compares sertraline (a common antidepressant) to a placebo (a pill with no medicine) to see which better reduces anxiety in children and teens who also have a neurodevelopmental disorder like autism, ADHD, or Tourette's. The goal is to help you and your child understand if this treatment might offer relief from anxiety.

This trial tests whether sertraline (an anti-anxiety medicine) helps children and teens with generalized, separation, and/or social anxiety disorders. It also includes healthy children/teens for comparison so researchers can better understand safety and symptoms over time.

This study tests whether using a cheek swab DNA test can help choose a better antidepressant for teenagers with anxiety or depression. The goal is to see if this personalized approach leads to fewer side effects and better results.

This study looks at genes, blood/brain proteins, and gut microbes in people with obsessive-compulsive disorder (OCD). It may help researchers understand what drives OCD and how treatments could be better tailored in the future.