Reducing vancomycin in NICU babies

This study looks at giving vancomycin continuously in the ICU or orthopedics for the first time, to see if the dosing is done correctly. If you’re an adult receiving this treatment, the trial may help improve how safely and accurately vancomycin is managed.

This early-phase study tests whether the antibiotic vancomycin can help children with primary sclerosing cholangitis or biliary atresia, and related gut/bile duct problems. It may work by changing gut bacteria, but you would need to avoid certain medicines beforehand.

This study looks at how the antibiotic vancomycin moves through and acts in newborn babies. It may help doctors dose the medicine more safely and effectively for babies in intensive care.

This study is a survey and quality-improvement effort in participating children’s intensive care units. It aims to understand and change how doctors decide to start vancomycin (an antibiotic) when sepsis is suspected, to improve care and avoid unnecessary use.

This study tests a personalized dosing approach for the antibiotic vancomycin given to patients in the neurological ICU. It aims to find the right dose for each patient to improve treatment and reduce side effects.

This trial tests a different way of giving vancomycin to children with sepsis to reduce the risk of kidney injury. It compares standard dosing to an approach that adjusts dose based on how the kidneys are working.