Clin2
NCT06774144Possibly a fitEnrolling by invitation

Rezafungin to prevent fungal infections in liver transplant patients

Liver Transplant InfectionFungal Infection

Part of Infections clinical trials.

This trial tests whether a medicine called rezafungin can help prevent serious fungal infections in people who have received a liver transplant. If you have certain risk factors, this study may offer extra protection against infections.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
385 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have had a liver transplant
  • You are 18 years old or older
  • You have at least one risk factor for fungal infection, such as a living donor transplant, a repeat transplant, a complex surgery, a specific type of bile duct connection, recent fungal infection, the need for kidney dialysis after transplant, or an additional surgery within 90 days of your transplant
  • You do not have an active fungal infection at the time of transplant
  • You are not allergic to echinocandin medicines
  • You are not pregnant

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03828773Recruiting
Azole antifungal prevention for leukemia during low white blood counts

This trial tests whether using a targeted antifungal medicine (aimed at PTX3) can better prevent serious fungal infections in adults with AML or a related bone marrow disease who will have very low neutrophils. It may help lower the risk of dangerous infections during intensive chemotherapy hospital stays.

Ghent, Belgium
NCT07080359Not yet recruiting
Study of an antifungal drug for ICU patients with fungal infections

This study tests a medicine called isavuconazole, which is used to treat serious fungal infections. It aims to see if it is safe and works well in very sick patients in the intensive care unit (ICU).

NCT05835479Recruiting· Phase 2
Rezafungin to treat Pneumocystis pneumonia in adults with HIV

This Phase 2 trial tests rezafungin, an antifungal medicine, to treat Pneumocystis pneumonia (PCP) in adults living with HIV. It may help people recover faster or more effectively from this serious lung infection.

Cape Town
NCT07135778Recruiting
Combination antifungal therapy for fungal infections in blood cancer

This trial tests a combination of antifungal medicines (liposomal amphotericin B and either isavuconazole or posaconazole) for people with blood cancers who develop a fungal infection despite taking preventive antifungal drugs. It aims to find a better treatment for these difficult infections.

Tianjin, Tianjin Municipality
NCT06640296Enrolling by invitation
Study on fungal infection prevention with liposomal amphotericin B

This trial looks at how a specific antifungal medicine, called liposomal amphotericin B, given over a longer period, helps prevent serious fungal infections in people undergoing treatment for cancer or receiving a stem cell transplant. It may be an option if you are at high risk for these infections.

Genoa
NCT07656493Not yet recruiting
Liposomal amphotericin B for transplant patients with fungal infections

This study looks at how well liposomal amphotericin B works for treating serious fungal infections in people who have had an organ transplant. It aims to understand the treatment's effectiveness and safety in a real-world setting.

Chengdu, Sichuan

Hear when a new Liver Transplant Infection trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.