Preventive PIPAC for advanced stomach cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests if a special type of chemotherapy delivered as a mist during surgery (PIPAC) can help prevent the spread of stomach cancer. It is for people with advanced but not yet metastatic stomach cancer who have not had prior treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have been diagnosed with stomach cancer that has grown into deeper layers (T3 or T4) but has not spread to distant organs (M0).
- You have not had any previous chemotherapy, radiation, or surgery for cancer.
- A recent laparoscopy showed no cancer cells in the fluid around your abdomen (negative peritoneal cytology).
- You are in generally good health (able to carry out daily activities, ECOG 0-2).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether adding a special type of chemotherapy sprayed directly into the abdomen (PIPAC) to standard chemotherapy is safer and works better for stomach cancer that has spread only to the lining of the abdomen.
This trial tests a combination of a special chemotherapy sprayed into the abdomen (PIPAC) and a minimally invasive surgery to remove the stomach in people with high-risk stomach cancer. The goal is to see if this approach can improve outcomes for patients whose cancer has grown into the stomach wall or spread to abdominal fluid but not to other organs.
This trial looks at a way to give chemotherapy into the abdomen (through a small tube during laparoscopy) for certain stomach cancers. It aims to see whether this approach improves cancer control and surgical outcomes for people whose tumors can potentially be removed.
This trial tests a treatment called PIPAC (medicine delivered into the abdomen through a small scope) along with “multimodal” therapy, including chemotherapy, for stomach cancer that has spread only in the lining of the abdomen in limited amounts. It may help control the cancer and prevent progression after surgery.
This trial tests a new way to deliver chemotherapy directly into the abdomen using a spray (called PIPAC) in people with stomach cancer that has spread to the lining of the belly. The aim is to see if it can help control the cancer with fewer side effects.
This trial tests a preventive treatment called PIPAC for people with colorectal cancer that has a high risk of spreading to the lining of the abdomen. PIPAC delivers chemotherapy directly into the abdomen during a short procedure to try to stop the cancer from coming back there.
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