GH56 capsule study for MTAP-deleted advanced solid tumors
Part of Cancer clinical trials.
This study tests an experimental capsule (GH56) for people whose advanced solid tumors have a specific genetic change called MTAP deletion. The goal is to see if the capsule is safe and helps shrink tumors.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- Your tumor has a specific genetic change called MTAP deletion (your doctor can check this)
- You have at least one tumor that can be seen and measured on a scan
- You are able to take care of yourself and are out of bed more than half the day (ECOG 0-1)
- You have not had major surgery or certain cancer treatments in the last 4 weeks
- You are willing to use birth control (if applicable) and follow study procedures
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new drug called GS-2426 for people with advanced solid tumors that have a specific genetic change called MTAP deficiency. It may be an option if other treatments have stopped working or are not available.
This trial tests a new tablet, DC50292A, for people whose cancer has an MTAP gene deletion. It is for patients whose cancer has spread or returned and who have not had success with other treatments.
This study tests a new drug, BMS-986504, to see how it is processed and removed from the body in people with certain advanced solid tumors. It is for patients whose cancer has a specific genetic change (MTAP deletion) and who have no other good treatment options.
This early-stage trial tests a new drug called HS-10587 in patients whose advanced cancers have a specific genetic feature (MTAP deletion) and have not responded to standard treatments. The drug may help slow or stop cancer growth.
This trial tests an experimental drug called BGB-58067, either alone or with other cancer treatments, for people with advanced solid tumors that have stopped responding to standard therapy. It may be an option if you have a specific genetic change (loss of MTAP) in your tumor.
This trial tests an experimental pill called SY-9453 for people with advanced solid tumors that have a specific genetic change (MTAP deletion). The goal is to see if it is safe and how the body processes it. It may be an option if you have tried standard treatments without success.
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