Clin2
NCT06797999Possibly a fitRecruiting

Study of ADCE-D01 for soft tissue sarcoma

Metastatic Soft Tissue SarcomaUnresectable Soft Tissue Sarcoma

Treatments studied

Part of Cancer clinical trials.

This trial tests a new drug called ADCE-D01 for people with soft tissue sarcoma that has spread or cannot be removed by surgery. The goal is to see if it is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
270 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must have soft tissue sarcoma that has spread or cannot be surgically removed.
  • You must have received at least 1 but no more than 2 types of chemotherapy for metastatic disease.
  • Your cancer must be measurable on scans.
  • You must be able to care for yourself (ECOG score 0 or 1).
  • You must have a life expectancy of at least 3 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03138161Recruiting· Phase 1/Phase 2
Testing three medicines for previously treated soft-tissue sarcoma

This trial tests trabectedin plus ipilimumab and nivolumab in people with advanced soft-tissue sarcoma that has already been treated. It aims to see how well this combination works and how safely it can be given.

Santa Monica, California
NCT06367075Recruiting· Phase 2
Cadonilimab plus adriamycin for advanced soft tissue sarcoma

This trial tests a combination of two drugs—cadonilimab (a type of immunotherapy) and adriamycin (chemotherapy)—for adults with advanced soft tissue sarcoma that hasn't been treated before. The goal is to see if this combination helps shrink tumors or slow their growth.

Wuhan, Hubei
NCT06597721Recruiting· Phase 1
ADCE-T02 for advanced solid tumors

This trial tests a new drug called ADCE-T02, which is an antibody-drug conjugate designed to target and deliver a chemotherapy payload to cancer cells that have a protein called tissue factor. The study is for people with advanced solid tumors that have not responded to other treatments, and it aims to see if the drug is safe and effective.

Rogers, Arkansas
NCT07156565Recruiting· Phase 1
Study of actinium therapy for advanced soft tissue sarcoma

This trial is testing a new type of radiation therapy for advanced soft tissue sarcoma that has not responded to other treatments. The goal is to see if this therapy can shrink tumors and help control the cancer.

Los Angeles, California
NCT07842276Not yet recruiting· Phase 2
Utidelone and doxorubicin for advanced soft tissue sarcoma

This study tests a combination of two chemotherapy drugs—utidelone and doxorubicin—for people with advanced soft tissue sarcoma. The goal is to see if this combination can help shrink or slow the cancer.

Chengdu
NCT07243626Recruiting· Phase 2
Envafolimab plus chemo for advanced soft tissue sarcoma

This trial tests a new immunotherapy drug (envafolimab) combined with two chemotherapy drugs (doxorubicin and ifosfamide) for people with advanced soft tissue sarcoma who have not had prior treatment. The goal is to see if this combination is safe and effective.

Hanzhong, Zhejiang

Hear when a new Metastatic Soft Tissue Sarcoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.