Testing three medicines for previously treated soft-tissue sarcoma
Treatments studied
Part of Cancer clinical trials.
This trial tests trabectedin plus ipilimumab and nivolumab in people with advanced soft-tissue sarcoma that has already been treated. It aims to see how well this combination works and how safely it can be given.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and have soft-tissue sarcoma that has spread or cannot be removed surgically
- You have already received anti-cancer treatment for your sarcoma
- You can have measurable tumors seen on scans, and your last scan shows “measurable disease”
- You are well enough to do daily activities (ECOG 0 or 1) and are expected to live at least 3 months
- Your blood, kidney, and liver tests are within the trial’s limits
- You can sign consent and will be able to follow all study visits and treatment plans
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a combination of chemo medicines (gemcitabine, doxorubicin, docetaxel) plus an immunotherapy drug (nivolumab) for advanced sarcoma that can’t be removed with surgery. It may help shrink tumors and slow disease growth in people whose cancer has already been treated and is measurable on scans.
This Phase 2 study tests a combination treatment for locally advanced or metastatic sarcoma that cannot be fully removed by surgery. It aims to shrink tumors and control disease by combining an injected cancer-killing medicine with two cancer-fighting drugs.
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