Nerve block and pulse radiofrequency for long-term shingles pain
Treatments studied
Part of Infections clinical trials.
This trial tests a combination treatment — a nerve block plus a type of focused energy called pulse radiofrequency — to see if it can relieve stubborn shingles pain that has lasted over a month. If you have this type of pain on your chest or back, this study may offer a new option to help reduce it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had shingles with a painful, blistering rash.
- The pain has lasted for more than one month despite trying usual treatments.
- Your pain is at least a 4 on a 0–10 scale (0 = no pain, 10 = worst pain).
- The pain is on your chest or upper back (from nerve roots in the thoracic area).
- You have not had other invasive pain procedures (like spinal cord stimulation) and do not have conditions like cancer, autoimmune disease, organ transplant, or a bleeding disorder.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a combination of two treatments to reduce shingles pain that hasn't responded to standard medicines. It involves a nerve block to see if it can help people who have ongoing pain after shingles.
This trial tests a two-step procedure for treating nerve pain after shingles (called postherpetic neuralgia). First, a special type of radiofrequency treatment is applied to block the pain signals. Then, a long-lasting numbing medicine is injected under the skin to help keep the pain away. It is for people aged 40 to 85 who have not gotten enough relief from standard medicines.
This study tests a combination of two treatments for long-term nerve pain after shingles: a medication called esketamine and a nerve block (pulsed radiofrequency) applied to the affected spinal nerves. The goal is to see if this combination relieves the burning or shooting pain better than the nerve block alone.
This study tests a safe, non-surgical treatment called transcutaneous pulsed radiofrequency to see if it can help reduce nerve pain that continues after shingles. It targets the painful area through pads on the skin.
This study tests whether adding a medicine called esketamine to a standard nerve block procedure can improve pain relief for people with shingles-related nerve pain. If you have had shingles pain for less than 3 months, this might help reduce pain and prevent long-term discomfort.
This trial compares two procedures—a nerve block injection and a radiofrequency treatment—to see which works better for lasting pain after shingles. It aims to help people with persistent pain in the neck, chest, or lower back.
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