Esketamine plus nerve treatment for shingles pain
Treatments studied
Part of Infections clinical trials.
This study tests a combination of a nasal spray medicine (esketamine) and a nerve treatment (pulsed radiofrequency) to reduce severe shingles pain. It may help people who have had shingles pain for less than 3 months and are already scheduled for the nerve procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- Your shingles rash started less than 90 days ago.
- The rash is on your neck, upper back, or lower back (spinal nerve areas).
- Your average pain is at least 4 out of 10.
- You are already planning to have a CT-guided pulsed radiofrequency (PRF) treatment for the nerve root.
- You are not pregnant, breastfeeding, or planning pregnancy, and you have no serious medical conditions like sleep apnea, immune disease, cancer, drug abuse, or certain mental health conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new pain medication called tulodesvenlafaxine for people with shingles-related pain. It may help if you have moderate to severe pain that started within the last 90 days.
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This study tests a combination of a nasal spray medicine (esketamine) and a minimally invasive procedure (pulsed radiofrequency treatment of the nerve root) to treat long-lasting pain from shingles (postherpetic neuralgia). It is for adults with moderate to severe pain that has persisted for more than 3 months.
This trial tests whether adding esketamine (a fast-acting pain medicine) to a standard nerve treatment called pulse radiofrequency (PRF) can better relieve lasting facial pain from shingles. It may help people who still have pain in the face or head after shingles.
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