Comparing two antidepressants for pain-related somatic symptom disorder
Treatments studied
Part of Mental health, Pain clinical trials.
This trial tests whether venlafaxine or dosulepin works better for people whose main problem is pain from a condition called somatic symptom disorder. You may join if you are 18–65, have not recently taken similar medication, and do not have other serious health issues.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with somatic symptom disorder where pain is the main symptom
- You are between 18 and 65 years old
- Your pain and other physical symptoms score (PHQ-15) is 5 or higher
- You have not taken any treatment for this condition in the last 4 weeks or have never been treated before
- You do not have any other serious medical problems like cancer, liver, kidney, heart, or lung disease
- You are not pregnant or breastfeeding, and you do not have a history of substance abuse
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether the antidepressant venlafaxine can help reduce chronic low back pain that has no clear physical cause. If you've had this type of pain for over 3 months and are not depressed, you may be eligible.
This study tests an experimental medication called toludesvenlafaxine to see if it can help people with long-lasting low back pain that has no clear cause. If you have moderate to severe lower back pain for more than 3 months and haven't taken antidepressants before, this may be an option for you to explore.
This trial compares two types of medicines—anti-convulsants and anti-depressants—for people with persistent pain lasting more than 3 months. It aims to find out which option works better in everyday care and for which patients.
This study tests whether the antidepressant venlafaxine, combined with education and behavioral therapy, can reduce bladder pain and urinary symptoms in people with bladder pain syndrome (also called interstitial cystitis). It aims to find a new treatment option that may improve daily comfort and quality of life.
This trial tests a combination of two medicines (pregabalin and venlafaxine) for people with fibromyalgia whose pain is moderate to severe and has not been helped enough by non-drug treatments. The goal is to see if the combination works better and is safe.
This study tests a combination of two medications (pregabalin and toludesvenlafaxine) to see if it is safe and effective for people with fibromyalgia whose pain has not improved with non-drug treatments and who have not yet tried standard medications for this condition.
Hear when a new Somatic Symptom Disorder (DSM-V) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.