Predicting outcomes of CDK4/6 inhibitors plus hormone therapy for advanced breast cancer
Treatments studied
Part of Cancer, Skin clinical trials.
This study looks at how well a type of targeted therapy (called CDK4/6 inhibitors) combined with hormone therapy works as the first treatment for advanced breast cancer that is hormone receptor-positive and HER2-negative. Researchers want to find patterns that could help predict which patients benefit most.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced breast cancer that is hormone receptor-positive (HR+) and HER2-negative (HER2-).
- You are about to start or have already started treatment with one of these drugs: palbociclib, ribociclib, or abemaciclib, combined with hormone therapy, as your first treatment for advanced cancer.
- You have not used a CDK4/6 inhibitor alone (without hormone therapy) for advanced disease.
- You have not used a CDK4/6 inhibitor as part of your treatment for early-stage (localized) breast cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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