Testing tenapanor for cystic fibrosis-related constipation
Treatments studied
Part of Digestive system, Genetic & congenital, Lungs & breathing clinical trials.
This study tests whether the drug tenapanor can help people with cystic fibrosis who have constipation. It may be an option for those whose current treatments are not working well.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed diagnosis of cystic fibrosis.
- You must have long-term constipation (at least 3 months) with specific symptoms like straining, hard stools, or fewer than 3 bowel movements per week.
- You must be willing to stop your current bowel medications for 2 weeks before starting the study drug (with a rescue laxative available if needed).
- You cannot have used antibiotics within the last 4 weeks (except stable azithromycin for lung health).
- You cannot have been hospitalized or had a bowel blockage in the last 4 weeks.
- You must not have taken tenapanor before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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