Clinical trials
Cystic Fibrosis clinical trials
Below are recruiting cystic fibrosis clinical trials, each written for real people, not researchers. We’re tracking 148 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03839992Recruiting
Checks for hidden small airways blockage in cystic fibrosis
This trial looks for early, “hidden” breathing test abnormalities in people with cystic fibrosis who have normal routine lung test results. It may help researchers find blockage in smaller airways before it shows up on standard tests.
Lakewood, CaliforniaAges 5–40 - NCT06284577Recruiting
Quality of life and gut health in children with cystic fibrosis
This study looks at how a drug called ETI (a combination of three medicines) affects the quality of life and gut health of children with cystic fibrosis. If you or your child has the right type of CF and is between 2 and 18 years old, this trial may help us understand how treatment improves daily life and digestion.
OsloAges 2–18 - NCT07809867RecruitingPhase 4
How Trikafta moves through the body in cystic fibrosis
This study looks at how the medicine elexacaftor/tezacaftor/ivacaftor (often called Trikafta) works in the body in people with cystic fibrosis. It helps doctors understand the right dose and how the drug is processed, which may improve treatment for children and adults.
GenovaAges 6 years+ - NCT07729787Recruiting
Autogenic drainage vs. chest percussion for kids with CF
This trial compares two breathing techniques to help clear mucus from the lungs of children with cystic fibrosis. It aims to see if one method (autogenic drainage) works better than another (mechanical percussion with a vest).
Multan Khurd, Punjab ProvinceAges 6–12 - NCT05099939Recruiting
Monitoring sugar changes in adults with cystic fibrosis
This study uses continuous glucose monitoring (a sensor that checks blood sugar trends) to understand how sugar handling changes over time in people with cystic fibrosis. It may help doctors spot early “pre-diabetes” or abnormal sugar patterns sooner.
Montreal, QuebecAges 18 years+ - NCT07569419RecruitingEarly Phase 1
Testing Linaclotide for Cystic Fibrosis Bowel Function
This early-stage study tests whether a medication called linaclotide can help improve bowel function in people with cystic fibrosis. Researchers will use MRI scans and other tests to see how the medication affects your digestive system.
NottinghamAges 18–65 - NCT07508904Recruiting
Exercise effects in children with cystic fibrosis
This study tests whether a specific exercise program can improve muscle strength, breathing, and fitness in children with cystic fibrosis who are stable and able to exercise.
LahoreAges 6–18 - NCT07484607Recruiting
Study on infections and treatments in cystic fibrosis exacerbations
This study looks at how lung infections and inflammation affect people with cystic fibrosis during severe flare-ups. It aims to understand which antibiotics work best and why, so your care team can choose the right treatment for you.
CardiffAges 16 years+ - NCT06132048Recruiting
Testing a smartphone app for cystic fibrosis
This study tests a smartphone app called MuCopilot that helps you track your cystic fibrosis symptoms at home. Researchers want to see if the app is easy to use and can give accurate information about your condition.
RouenAges 18 years+ - NCT05802264RecruitingPhase 1
Inhaled amphotericin B for healthy volunteers and cystic fibrosis
This early-phase study tests how different doses of an inhaled medicine (amphotericin B) work and are tolerated. It includes healthy adults and people with cystic fibrosis (CF) to see if the dose schedule is safe and potentially beneficial.
Canberra, Australian Capital TerritoryAges 16 years+ - NCT06836453Recruiting
New sweat test for cystic fibrosis diagnosis
This trial tests a new device that measures how your sweat glands react to a common asthma medication. It aims to better classify people with cystic fibrosis or related diseases, and also includes healthy volunteers and carriers.
BrusselsAges Any age - NCT07363304Recruiting
How ETI therapy affects body and gut in cystic fibrosis
This study looks at how the triple combination therapy (elexacaftor/tezacaftor/ivacaftor, or ETI) affects your body's metabolism, epigenetics, and gut bacteria in people with cystic fibrosis. It aims to understand the broader health benefits of this treatment.
Bari, BariAges 2 years+ - NCT07342920Recruiting
Smoking and vaping in adults with cystic fibrosis
This study looks at how many adults with cystic fibrosis smoke or vape (use e-cigarettes). It aims to understand how common these habits are in this group.
StrasbourgAges 18 years+ - NCT07223255Recruiting
Mediterranean diet study for children with cystic fibrosis
This study tests whether a Mediterranean-style diet can improve gastrointestinal health in children with cystic fibrosis. It requires families to follow the diet for 6 months and attend regular clinic visits.
Lebanon, New HampshireAges 3–18 - NCT07192679Recruiting
MAGNIFY Study: New MRI for cystic fibrosis lung health
This study tests a new type of MRI scan that uses either special gas (xenon) or regular MRI to take detailed pictures of the lungs in people with cystic fibrosis. The goal is to see how well these scans can track lung health over time, without using X-ray radiation.
SheffieldAges 1 year+ - NCT06364176RecruitingPhase 2
Adding losartan to improve Trikafta response in CF
This study tests whether adding the blood pressure medication losartan can help the standard CF drug Trikafta work better by reducing inflammation. It's for people with CF who still have high sweat chloride levels despite taking Trikafta.
Kansas City, KansasAges 12 years+ - NCT06984679Recruiting
Physical function study for kids with cystic fibrosis
This trial compares physical abilities between children with cystic fibrosis and healthy children. It aims to find differences that could lead to better care and therapies.
IzmirAges 6–18 - NCT06950892Recruiting
Remote sputum collection study for cystic fibrosis
This study tests if people with cystic fibrosis can collect sputum samples at home and mail them in, instead of coming to the clinic. It aims to make participation easier for patients.
Denver, ColoradoAges 18 years+ - NCT06940531Recruiting
Tracking causes of lung flare-ups in cystic fibrosis
This study aims to understand what causes and increases the risk of lung infections (exacerbations) in people with cystic fibrosis. It involves regular monitoring and sample collection at home and in the clinic to identify early warning signs.
Manchester, ManchesterAges 5 years+ - NCT06747858RecruitingPhase 2
Testing a new inhaler medicine for cystic fibrosis
This study tests an experimental inhalable medicine called ARCT-032 for people with cystic fibrosis who cannot take or benefit enough from current CFTR modulators. The goal is to see if it safely improves lung function and quality of life.
Tucson, ArizonaAges 18 years+ - NCT05723445Recruiting
Low glycemic diet test for diabetes and body changes in CF
This trial studies whether a low glycemic load (a specific way of choosing carbohydrates) improves blood sugar control and body composition in adults with cystic fibrosis–related diabetes. It may help reduce blood sugar problems and support healthier weight and body measurements.
Boston, MassachusettsAges 18–70 - NCT06616857Recruiting
Smartphone app to boost activity in teens with CF
This study tests a personalized smartphone app to help teens and young adults with cystic fibrosis be more active. The app provides tailored tips and support to encourage daily physical activity.
Jacksonville, FloridaAges 13–25 - NCT06560463Recruiting
CGM and glucose test for cystic fibrosis related diabetes
This study tests if a continuous glucose monitor (CGM) along with a standard glucose drink test can better detect diabetes in people with cystic fibrosis. It is for adults who do not yet have diabetes and are generally healthy.
Milwaukee, WisconsinAges 18 years+ - NCT06507956Recruiting
Physical activity and sitting habits in adults with cystic fibrosis
This study looks at how physically active and sedentary adults with cystic fibrosis are. It uses a device to measure your daily movement and asks you to fill out a few questionnaires. The goal is to better understand your activity patterns and find ways to help you stay healthy.
Pierre-BéniteAges 18–65
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Cystic Fibrosis trials by city
Studies with a site in or near these metro areas.
Cystic Fibrosis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for cystic fibrosis?
- Yes. Clin2 currently lists 148 recruiting cystic fibrosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cystic fibrosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cystic fibrosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.