Clin2
NCT06813365Possibly a fitRecruiting

A targeted therapy for EGFR-mutated advanced lung cancer

Nonsmall-cell Lung Cancer

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial is testing a new targeted pill for people with EGFR-positive non-small cell lung cancer. It's designed for those whose cancer has grown after other treatments, and it works by blocking a specific protein that helps the cancer grow.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
300 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have been told that your lung cancer has an EGFR change that is known to respond to targeted treatment.
  • You have had at least one previous treatment for your lung cancer.
  • You are in generally good health overall (able to be up and about).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05559645Recruiting
Oral drug trial for EGFR-mutated lung cancer after prior treatment

This trial studies an oral (by mouth) EGFR-blocking medicine (DZD9008) in people with advanced lung cancer that has EGFR mutations. It’s for cancers that have grown despite standard treatment or couldn’t be tolerated, and aims to control the cancer while keeping side effects manageable.

Beijing, Beijing Municipality
NCT07079475Recruiting· Phase 1/Phase 2
Study of two targeted pills for EGFR-mutated lung cancer

This trial tests a new combination of two oral targeted drugs for people with advanced non-small cell lung cancer that has an EGFR mutation. It may help if you have already been treated with a third-generation EGFR pill or if you are starting treatment for the first time.

Beijing, Beijing Municipality
NCT05536505Recruiting· Phase 2
After-surgery targeted pill to prevent relapse in EGFR lung cancer

This Phase 2 trial studies whether an EGFR-targeted pill, given after surgery, can reduce the chance of lung cancer coming back. It specifically looks at people whose tumors have certain EGFR changes and where “minimal residual disease” (tiny leftover cancer) is being used to guide treatment.

Beijing
NCT07070440Recruiting· Phase 1/Phase 2
New combination therapy for advanced EGFR-mutated lung cancer

This trial tests a new combination therapy (DZD6008 plus other drugs) for people with advanced lung cancer that has an EGFR mutation and has stopped responding to a third-generation targeted therapy. It aims to find a better treatment option for these patients.

Shanghai, Shanghai Municipality
NCT06295432Recruiting· Phase 2
Study of two targeted drugs for EGFR-mutated lung cancer

This trial tests a combination of two targeted drugs (DZD9008 and AZD4205) for people with advanced non-small cell lung cancer that has a specific EGFR mutation and has stopped responding to standard treatments. The goal is to see if this combination can shrink tumors or slow cancer growth.

Guangzhou, Guangdong
NCT06905197Recruiting· Phase 1
Study of DZD6008 for advanced NSCLC with EGFR mutations

This trial tests an oral drug called DZD6008 for people with advanced non-small cell lung cancer (NSCLC) that has certain EGFR mutations. It may be an option for those who have tried other EGFR treatments or are new to treatment.

New York, New York

Hear when a new Nonsmall-cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.