Removing large colon polyps: one piece vs. multiple pieces
Part of Cancer, Digestive system clinical trials.
This trial compares two ways to remove large, flat polyps (granular type) from the colon or rectum: one that removes the polyp in one piece (endoscopic submucosal dissection) and one that removes it in pieces (endoscopic mucosal resection). The goal is to see which method has a lower chance of the polyp coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a large (≥20 mm) flat polyp called a laterally spreading tumor, granular type (LST-G) in the colon or rectum.
- Your doctor plans to remove the polyp using a scope (endoscopic resection).
- You are expected to live more than 10 more years (your doctor can estimate this).
- You do not have a different type of polyp (LST-NG), or one with depressed areas, or a certain high-risk pattern (Kudo Vi or Vn).
- You do not have inflammatory bowel disease (like Crohn's or ulcerative colitis) or a hereditary polyp syndrome (like FAP or Lynch).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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