Natural killer cell therapy for infertility and pregnancy problems
Part of Women’s health & pregnancy clinical trials.
This study tests a treatment using your own immune cells (natural killer cells) to improve pregnancy chances. It's for women with infertility, repeated miscarriages, or other pregnancy complications linked to abnormal natural killer cell function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have abnormal natural killer cell function in your uterus.
- You have had at least 2 unexplained miscarriages, repeated IVF failure, or infertility for unknown reasons.
- You have clear plans to get pregnant.
- Your ovaries work normally or you have frozen embryos available.
- You are between 18 and 30 in body mass index (BMI).
- Your uterine lining is at least 7mm thick on ultrasound.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests an experimental therapy using your own special immune cells (called decidual-like natural killer cells) to improve the chances of a successful pregnancy for people who have had reproductive failure. The treatment is given to help the uterus become more receptive to embryo implantation.
This trial tests a new therapy that uses your own natural killer (NK) cells, modified to better fight cancer and injected directly into your abdomen. It's for people with advanced ovarian cancer who cannot have surgery or whose tumor cannot be fully removed.
This trial tests a new immune cell therapy called NK521 for people with advanced solid tumors like liver or ovarian cancer that have not responded to standard treatment. The therapy may be given as an infusion or into the belly (for those with fluid buildup containing cancer cells).
This study tests whether adding your own natural killer (nk) cells (a type of immune cell) to your regular treatment helps fight non-hodgkin lymphoma that has come back or not responded. The goal is to see if this extra treatment is safe and works better at stopping the cancer.
This trial tests a new type of immune cell therapy (CIML NK cells) given directly into the abdomen for women with ovarian cancer that has come back and is now resistant to standard platinum chemotherapy. The goal is to see if these specially trained cells can fight the cancer safely.
This study gives a small amount of your own immune cells into the uterus to change the immune environment in the uterine lining. It aims to improve how the uterine lining supports implantation, especially for people trying to conceive with embryo transfer of normal (euploid) embryos.
Hear when a new Infertility Unexplained trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.