Autologous natural killer cell therapy for reproductive failure
Part of Women’s health & pregnancy clinical trials.
This study tests an experimental therapy using your own special immune cells (called decidual-like natural killer cells) to improve the chances of a successful pregnancy for people who have had reproductive failure. The treatment is given to help the uterus become more receptive to embryo implantation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had reproductive failure (such as repeated miscarriages or failed implantation) and have abnormal natural killer (NK) cells in your menstrual blood.
- You are currently trying to conceive.
- You either have normal ovarian function, or you have premature ovarian insufficiency with at least 2 high-quality frozen embryos ready for transfer.
- Your uterine lining (endometrium) is at least 7 mm thick, measured by ultrasound around the time of ovulation.
- Your body mass index (BMI) is between 18 and 28 kg/m².
- You are willing to follow the study's follow-up plan and do not have any of the excluded conditions (such as severe endometriosis, certain uterine abnormalities, uncontrolled autoimmune or endocrine disorders, history of cancer, or allergy to blood products).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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